Dezembro 22 - Lista do mês

ARA - Aumento de Risco Absoluto | ECA - Ensaio clínico aleatorizado | ITA - Intention-to-treat Analysis | MA - Meta-análise | MBE - Medicina baseada na evidência | NNH - Number needed to harm | NNT - Number needed to treat | PPA - Per protocol analysis | RRA - Redução do Risco Absoluto | RS - Revisão Sistemática

META-REVISÃO

Meta-investigação e MBE

Spin within SR abstracts on antiplatelet therapies after acute coronary syndrome | BMJ Open

REVISÕES SISTEMÁTICAS de ECAs

COVID-19

Awake prone positioning in covid-19 related hypoxemic respiratory failure | The BMJ

Infecciologia, Microbiologia & Antimicrobianos

Azithromycin vs placebo to treat LRTIs associated with low procalcitonin | Lancet Infectious Diseases

Meta-investigação & MBE

Quality of reporting of RCTs of artificial intelligence in healthcare: a systematic review | BMJ Open

Neurologia

Vestibular suppressants for benign paroxysmal positional vertigo | AcEM

Ler: What’s the Best Treatment for Peripheral Vertigo?

Efficacy and Safety of IV Thrombolysis and Thrombectomy Among Wake-Up Stroke | AEM

Ler: Concise Review of Lytics and Endovascular Therapy for ‘Wake Up’ Stroke – JournalFeed

Oncologia

ALK inhibitors in ALK-rearranged non-small cell lung cancer w/ and wo/ brain metastases | BMJ Open

Erlotinib plus bevacizumab vs erlotinib in EGFR+ advanced non-small-cell lung cancer | BMJ Open

ICIs in Advanced Esophageal Squamous Cell Carcinoma w/ Low PD-L1 Subgroups | JAMA Oncology

ENSAIOS CONTROLADOS E ALEATORIZADOS

Cardiovascular

Pharmacist-Led Telehealth vs Clinic-Based Care for Uncontrolled High Blood Pressure | Hypertension

Cirurgia, Ortopedia & MFR

Motion control vs neutral walking footwear on pain in lateral tibiofemoral joint OA| BMJ Open

COVID-19

Favipiravir in patients hospitalised with COVID-19 - PIONEER trial | The Lancet Respiratory Medicine

Molnupiravir plus usual care vs usual care for early high-risk COVID-19 - PANORAMIC | Lancet

High dose steroids in hospitalised COVID19 w/ hypoxia wo/ ventilatory support - RECOVERY|medRxiv

COVID-19 Vaccine Messaging Platforms in EDs on Vaccine Acceptance and Uptake | JAMA IM

Long-term (180-Day) Outcomes in Critically Ill COVID-19 Patients - REMAP-CAP | JAMA

Anticoagulation Strategies in Non–Critically Ill Patients with Covid-19 | NEJM Evidence

Dermatologia

Anti-OX40 Rocatinlimab in moderate-to-severe atopic dermatitis | The Lancet

Gastroenterologia & Hepatologia

2nd-line levofloxacin-based vs bismuth-based quadruple therapy for Hp eradication | Lancet G&H

Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis | NEJM

Community-Based Physical Activity Program for Type 2 Diabetes | JAMA Network Open

Community Health Worker–Delivered Personal Sound Amplification Device on Self-Perceived Communication Function in Older Adults With Hearing Loss | JAMA

Biopsychosocial or Postural Therapy on Acute and Subacute Spine Pain | JAMA

Imuno-mediadas

Bimekizumab in psoriatic arthritis, naive to biologic treatment - BE OPTIMAL | The Lancet

Bimekizumab in active psoriatic arthritis refractory to TNFα-inhibitors - BE COMPLETE | The Lancet

Infecciologia, Microbiologia & Antimicrobianos

Rezafungin vs caspofungin for treatment of candidaemia and invasive candidiasis - ReSTORE | Lancet

Colistin Monotherapy vs Combination Therapy for Carbapenem-Resistant Organisms |NEJM Evidence

Meta-investigação & MBE

Feedback on Clinical Reasoning Competence Among Medical Students | JAMA Network Open

Nefrologia

Intervention to Improve Decision Making for Older Patients With Advanced CKD (Stages 4-5) | AIM

Neurologia

Safety/efficacy of tenecteplase in wake-up stroke assessed by non-contrast CT, TWIST | Lancet Neuro

Oncologia

Immediate surgery vs NeoA (gemcitabine+capecitabine, FOLFIRINOX or chemoradio) - ESPAC5 |LG&H

NORMAS DE ORIENTAÇÃO CLÍNICAS - GUIDELINES

Infecciologia, Microbiologia & Antimicrobianos

Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults - IAS-USA | JAMA

Pneumologia

2023 GOLD Report - Global Initiative for Chronic Obstructive Lung Disease - GOLD (goldcopd.org)

ESTUDOS OBSERVACIONAIS

RS COM ESTUDOS OBSERVACIONAIS (com ou sem ECA)

Doente crítico/urgente

Diagnostic Errors in the Emergency Department: Systematic Review | Effective Health Care Program

Infecciologia, Microbiologia & Antimicrobianos

Pneumococcal urinary antigen tests for patients with ARF and suspected pneumonia | BMJ Open

Social norm feedback on antibiotic prescribing and behaviour change techniques - | Lancet ID

Human rabies despite post-exposure prophylaxis - The Lancet Infectious Diseases

Pregnancy outcomes after first-trimester artemisinin vs non-artemisinin antimalarials | Lancet

Prognostic factors for streptococcal toxic shock syndrome | BMJ Open

Meta-investigação & MBE

Guidelines for Reporting Outcomes in Trial Reports: The CONSORT-Outcomes 2022 Extension | JAMA

Neurologia

Blood-Based Biomarkers in Adults With Peripheral Neuropathies | JAMA Network Open

Head CT in Geriatric ED Patients with Delirium, Altered Mental Status, and Confusion | AEM

Hearing Aids and Cochlear Implants w/ Cognitive Decline and Dementia | JAMA Neurology

SUB-ANÁLISES DE ECAs

Oncologia

Tucatinib + Trastuzumab/Capecitabine for Refractory HER2 BreastCancer w/ BrainMetastases | JAMA

COORTE, CASO-CONTROLO & COORTE TRANSVERSAL

Cardiovascular

Soluble CD146 in intravascular and tissue congestion in acute dyspnoea - analysis of LEDA | BMJOpen

Critical reassessment of the individual patient meta-analysis on bypass grafts by Gaudino et al

Rapid Exclusion of AMI w/ single hs-TnT in the ED: A Multicenter US Evaluation | CIRCULATION

Seamens’ Sign: a novel electrocardiogram prediction tool for left ventricular hypertrophy | PeerJ

Cirurgia, Ortopedia & MFR

Surgeon-Delivered Nerve Block for Less Perioperative Pain & Opioid Use on Spine Surgery | JAMA NO

Oxygen administration during surgery and postoperative organ injury: ohort study | The BMJ

COVID-19

Diagnostic yield of screening for SARS-CoV-2 among patients admitted to hospital | BMJ Open

Post-COVID 12 Weeks after Omicron and Vaccination compared to Negative Controls | CID

Association of SARS-CoV-2 w/ Patient-Reported Well-being 3M After Symptomatic Illness | JAMA NO

Extent and nature of duplication in PROSPERO using COVID-19-related registrations | BMJ Open

Doente crítico/urgente

Inhaled Nitric Oxide vs Epoprostenol During Acute Respiratory Failure - CHEST

Haemodynamic effects of 10-min high inspired O2 concentration in the ED | BMJ Open

Comparison of YEARS and Adjust-Unlikely D-dimer Testing for Pulmonary Embolism in the ED | AEM

Implementation of the Modified Canadian C-Spine Rule by Paramedics | AEM

Geral, Geriatria & Paliativos

Association of 5α-Reductase Inhibitors w/ Dementia, Depression, and Suicide | JAMA Network Open

Infecciologia, Microbiologia & Antimicrobianos

Linezolid and Risk of Serotonin Syndrome in Patients Receiving Antidepressants | JAMA NetOpen

Effect of the acute phase on absorption of oral antibiotics in non-critically hospitalized patients | JAC

Impact of palliative care consultation on antibiotic overuse in terminal cancer at the end of life | JAC

Meta-investigação & MBE

Diagnostic Reasoning and the Accuracy of Findings in the History and Physical Examination

Clinical Study Results Reported in medRxiv Preprints vs Peer-reviewed Journal | JAMA Network Open

Retracted papers originating from paper mills: cross sectional study | The BMJ

Neurologia

Delayed ICH after head injury among elderly patients on anticoagulation seen in the ED | CJEM

Repeat Posttraumatic Brain CT in Elderly w/ Minimal Head Trauma and Antithrombotic Use | AEM

Antiepileptic Drugs and Incident Parkinson Disease in the UK Biobank | JAMA Neurology

Endovascular Thrombectomy vs Medical Management Beyond 24 Hours | JAMA Neurology

Oncologia

Yield of Surveillance Imaging After Mastectomy in Prior Breast Cancer | JAMA Network Open

ANÁLISE ECONÓMICA

Cardiovascular

Compression Therapy w/ Early Endovenous Ablation in Venous Ulceration | JAMA Network Open

INQUÉRITOS / QUALITATIVOS

Geral, Geriatria & Paliativos

Experiences of palliative / geriatric non-operative management of hip fracture patients | BMJ Open

CASO CLÍNICO / IMAGEM CLÍNICA

Cardiovascular

A Case of Isolated Cardiac Sarcoidosis | Annals of Internal Medicine

“Trench Foot” on the Banks of Lake Geneva: A Severe Case of Nonfreezing Cold Injury | AIM

• ECG

  • A Peculiar ST Elevation Mimicking STEMI | JAMA Internal Medicin

Dermatologia

Cachexia and Diffuse “Fish-Scale” Skin | Annals of Internal Medicine

Gastroenterologia & Hepatologia

Ruptured Hepatic Subcapsular Hematoma after Heparin for Submassive Pulmonary Embolism | AIM

Imuno-mediadas

Severe Cervicodynia in a Patient With Pustules on the Palms | JAMA Neurology

Infecciologia, Microbiologia & Antimicrobianos

A Case of Multiple Skin Lesions After LipodissolveTM Injection | Annals of Internal Medicine

Kaposi Sarcoma: A Forgotten Complication in Well-Controlled HIV | Annals of Internal Medicine

Nefrologia

Page Kidney From Ruptured Mycotic Pseudoaneurysm of Renal Artery | Annals of Internal Medicine

Neurologia

Recurrent Cryptogenic Stroke in a Young Woman: Congenital TTTP Unmasked | Annals of IM

OPINIÃO

REVISÃO NÃO-SISTEMÁTICA / NARRATIVA

Geral, Geriatria & Paliativos

Gabapentin Will Not Cure the Opioid Crisis | JAMA Internal Medicine

Infecciologia, Microbiologia & Antimicrobianos

When and How to Use MIC in Clinical Practice? | Antibiotics

Meta-investigação & MBE

Is a one-size-fits-all ‘12-month rule’ appropriate to the last search date in SR? | BMJ EBM

PERSPECTIVA

Cardiovascular

NEJM Journal Watch Cardiology Top Stories of 2022 (jwatch.org)

COVID-19

The Tragedy of COVID19 | Sensible Medicine

Hematologia

Persistent challenges with treating multiple myeloma early | Blood - ASH

Infecciologia, Microbiologia & Antimicrobianos

Chaos in the Diagnosis of Pneumocystis Pneumonia - HIV and ID Observations

Meta-investigação & MBE

Analysis of cluster randomised trials as individually randomisation - Lancet Diabetes & Endocrinology

The limits of shared decision making | BMJ Evidence-Based Medicine

Neurologia

The Scent of Flavor | Linda Bartoshuk | Inference (inference-review.com)

Oncologia

The Tragedy of Oncology | Sensible Medicine

FDA Struggle to Withdraw Makena: Problems With the Accelerated Approval Process | JAMA

Preapproval Promises to Voluntarily Withdraw FDA-Approved Drugs | JAMA

Accelerated Approval Pathway: What Gives? - Chadi Nabhan | Sensible Medicine

FOAMed

Doente crítico/urgente

EMCrit 337 – Procedural Deep Dive – Lumbar Puncture (LP) | EMCrit

Laceration evidence: absorbable sutures or not? - First10EM

How far should sutures be spaced? - First10EM

Laceration evidence part 7: Aftercare instructions - First10EM

EMCrit 339 - Decisions, Decisions, Decisions with Andrew Petrosoniak

What's the down time? St Emlyn's • St Emlyn's (stemlynsblog.org)

Massive transfusion protocol: what is it, why does it exist, and when should I call one? - CanadiEM

Gastroenterologia & Hepatologia

Episode 62 – Connected Bilirubin – The Curious Clinicians

Geral, Geriatria & Paliativos

Handout #373 Recap Extravaganza 2022 - Curbsiders

Hope: At the Bedside Segment | Core IM Podcast

Imuno-mediadas

Episode 61 – Of ticks, alpha-gal, and red meat allergies – The Curious Clinicians

Infecciologia, Microbiologia & Antimicrobianos

The Bug Name Emoji Game | IDS

REBEL Core Cast 92.0 - Perichondritis - REBEL EM - Emergency Medicine Blog

Nefrologia

Keep Calm and Carry on Inhibiting the RAS — NephJC

Neurologia

PulmCrit Blogitorial - SIESTA syndrome: Sedation Induced EEG Suppression with Transient Agitation

The efficacy and safety of orexin antagonists for insomnia - #328 Tools for Practice

Pneumologia

Bronchodilators or inhaled steroids for post-infectious cough - #329 Tools for Practice