Outubro de 2024 - Inventário do mês

Vide também no Substack

Versão esquemática de Mariana Barosa:

What multimorbidity shows us about guideline-driven evidence based medicine ou Sensible Medicine

TABELA DE CONTÉUDOS:

1. META-REVISÃO

2. REVISÕES SISTEMÁTICAS DE ENSAIOS CONTROLADOS E ALEATORIZADOS (ECAs)

3. ENSAIOS CONTROLADOS E ALEATORIZADOS (ECAs)

4. NORMAS DE ORIENTAÇÃO CLÍNICA

5. OBSERVACIONAIS

   1. Revisões Sistemáticas

   2. Primários

   3. Casos clínicos e séries

6. OPINIÃO

   1. Revisões narrativas

   2. Perspectiva

   3. Notícias

7. FOAMed

Glossário:

✔✔✔ --> Muito relevante

✔ --> Relevante

? --> Relevante e dúvidas quanto à eficácia

✗ --> Não eficaz mas relevante (contraria hipóteses, práticas, etc.)

(sem símbolo) --> Pouco relevante (mas eventualmente interessante)

(sem símbolo) --> Não eficaz e pouco relevante (mas eventualmente interessante)

classificação pessoal, nem todos concordarão

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META-REVISÃO

Meta-investigação & MBE

Mobile phone interventions to improve health outcomes among patients with chronic diseases | Lancet Digital Health

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REVISÕES SISTEMÁTICAS de ECAs

tabela de conteúdos ↟

Cardiovascular

✔✔✔ Short-Term Dual Antiplatelet Therapy After Drug-Eluting Stenting in Patients With ACS | JAMA Cardiology

Doente crítico/urgente

✔✔✔ Leg Cycle Ergometry in Critically Ill Patients — Updated Systematic Review and Meta-Analysis | NEJM Evidence

Imuno-mediadas

Leukotriene receptor antagonists as add-on therapy to antihistamines for urticaria | JACI

Infecciologia, Microbiologia & Antimicrobianos

✔ Intermittent versus Daily Trimethoprim/Sulfamethoxazole Regimens for Pneumocystis Pneumonia Prophylaxis | OFID

✔ Oral versus intravenous antibiotic therapy for Staphylococcus aureus bacteremia or endocarditis | CID

Efficacy and safety of higher dose rifampicin in adults with presumed drug-susceptible tuberculosis | Lancet eCM

Nefrologia

✔✔✔ Haemodiafiltration versus haemodialysis for kidney failure: an individual patient data meta-analysis | Lancet

Neurologia

✔ Comparative effects of drug interventions for the acute management of migraine episodes in adults | BMJ

Oncologia

Correlation between ALK+ non-small cell lung cancer targeted therapy and thrombosis | BMJ Open

Effectiveness of immune checkpoint inhibitors alone or with others in advanced mucosal melanomas | Lancet eCM

Pneumologia

✔ Inhaled Reliever Therapies for Asthma: A Systematic Review and Meta-Analysis | JAMA

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ENSAIOS CONTROLADOS E ALEATORIZADOS

tabela de conteúdos ↟

Cardiovascular

✔✔✔ Arm Position and Blood Pressure Readings - ARMS | JAMA Internal Medicine

?✔? Vutrisiran in Patients with Transthyretin Amyloidosis with Cardiomyopathy - HELIOS-B | NEJM

??? PCI in patients undergoing transcatheter aortic-valve implantation - NOTION-3 | NEJM

Amiodarone or Implantable Cardioverter-Defibrillator in Chagas Cardiomyopathy - CHAGASICS | JAMA Cardiology

Cirurgia, Ortopedia & MFR

Total Hip Replacement or Resistance Training for Severe Hip Osteoarthritis - PROHIP | NEJM

Extracorporeal Blood Purification and Acute Kidney Injury in Cardiac Surgery - SIRAKI02 | JAMA

Dermatologia

Diagnóstico e Raciocínio Clínico

Doente crítico/urgente

✔✔✔ Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury - TRAIN | JAMA

✗ Effect of Tele-ICU on Clinical Outcomes of Critically Ill Patients - TELESCOPE | JAMA

Intraosseous vs intravenous vascular access in upper extremity among out-of-hospital cardiac arrest - VICTOR | BMJ

Frequency of Screening and Spontaneous Breathing Trial Techniques - FAST trial | JAMA

Endocrinologia

Gastroenterologia & Hepatologia

Phase 2 Trial of Anti-TL1A Monoclonal Antibody Tulisokibart for Ulcerative Colitis - ARTEMIS-UC | NEJM

Geral, Geriatria & Paliativos

✔ Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis - STEP 9 | NEJM

Assessment of clinical effectiveness of 3-step hand hygiene technique vs 6-step hand hygiene technique | OFID

Results after Four Years of Screening for Prostate Cancer with PSA and MRI - GÖTEBORG-2 | NEJM

Hematologia

Imuno-mediadas

✔ Infliximab versus Cyclophosphamide for Severe Behçet’s Syndrome - ITAC | NEJM Evidence

Infecciologia, Microbiologia & Antimicrobianos

✔ Aztreonam–avibactam vs meropenem for serious infections caused by Gram-negative bacteria - REVISIT | Lancet ID

✔ Switching to dolutegravir/lamivudine in suppressed HIV on bictegravir/emtricitabine/tenofovir - DYAD | OFID

Meta-investigação & MBE

Nefrologia

Neurologia

✔ Tongxinluo and Functional Outcomes Among Patients With Acute Ischemic Stroke - TISS | JAMA Network Open

✔ Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation - OPTIMAS | Lancet

Oncologia

✗ Phase 3 Trial of Stereotactic Body Radiotherapy in Localized Prostate Cancer - PACE | NEJM

Induction chemotherapy plus standard chemoradiotherapy in locally advanced cervical cancer - INTERLACE | Lancet

Pneumologia

rTMS as a next step in antidepressant nonresponders | American Journal of Psychiatry

Antidepressant incomplete and non-responders with treatment resistant depression - ASCERTAIN-TRD | Molecular Psy

Integrated mental health video consultations for people with depression or anxiety in primary care - PROVIDE-C | BMJ

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NORMAS DE ORIENTAÇÃO CLÍNICAS - GUIDELINES

tabela de conteúdos ↟

Cirurgia, Ortopedia & MFR

AHA/ACC/ACS/ASNC/HRS/SCA/SCCT/SCMR/SVM - Perioperative cardiovascular management for noncardiac surgery

Gastroenterologia & Hepatologia

✔ ACG clinical guideline: Treatment of Helicobacter pylori infection | American Journal of Gastroenterology

Neurologia

✔ 2023 U.S. DVA and U.S. DoD Clinical Practice Guideline for the Management of Headache | AIM

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ESTUDOS OBSERVACIONAIS

REVISÕES SISTEMÁTICAS COM ESTUDOS OBSERVACIONAIS (com ou sem ECA)

tabela de conteúdos ↟

Geral, Geriatria & Paliativos

✔ Height and lung cancer risk: A meta-analysis of observational studies | PLoS One

✗ Long-Term Use of Muscle Relaxant Medications for Chronic Pain: A Systematic Review | JAMA Network Open

Infecciologia, Microbiologia & Antimicrobianos

✗ A systematic review of nirmatrelvir/ritonavir and molnupiravir for the treatment of COVID-19 | OFID

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PRIMÁRIOS - SUB-ANÁLISE / COORTE / CASO-CONTROLO / INQUÉRITOS / A. ECONÓMICAS

tabela de conteúdos ↟

Cardiovascular

✔ Sudden cardiac death after myocardial infarction: individual participant data from pooled cohorts | EHJ

Doente crítico/urgente

✔ Early intramuscular adrenaline is associated with improved survival from out-of-hospital cardiac arrest | Resuscitation

Neurologia

Subarachnoid haemorrhage in the emergency department - SHED | European Medical Journal

Endocrinologia

✔Continuous glucose monitoring and duration of hypoglycaemia: an exploratory analysis of ONWARDS 1 | Lancet D&E

Epidemiological patterns of thyroid cancer and overdiagnosis in 2013–17 in 63 countries worldwide | Lancet D&E

Gastroenterologia & Hepatologia

Food Retention at Endoscopy Among Adults Using Glucagon-Like Peptide-1 Receptor Agonists | JAMA Network Open

Geral, Geriatria & Paliativos

✔ Association between exposure to PPIs and delirium: descriptive & disproportionality analysis of VigiBase | BMJ Open

Imuno-mediadas

✗ Application of Risk-Based Cancer Screening in Patients With Dermatomyositis | JAMA Dermatology

Infecciologia, Microbiologia & Antimicrobianos

✔ S. aureus bacteraemia following implantation of cardiac implantable electronic devices: Danish cohort | OFID

Continuous versus intermittent antimicrobial therapy infusions in inpatient and outpatient care - RWD in Finnland | BMJ

Characteristics of Streptococcal Toxic Shock Syndrome Caused by Different Beta-Hemolytic Streptococci Species| OFID

Two short standardised regimens for the treatment of rifampicin-resistant tuberculosis - STREAM stage 2 | Lancet RM

Listeriose: A Experiência de um Centro Hospitalar Português | RSPMI

Meta-investigação & MBE

✔✔✔ Do infographics ‘spin’ the findings of health and medical research? | BMJ-EBM

✔ Artificial Intelligence–Supported Development of Health Guideline Questions | Annals of Internal Medicine

✔ How professional development can be supported for health and care research methodologists-PROSPER | BMJOpen

Nefrologia

Antihypertensive drug treatment and the risk for intrahemodialysis hypotension | CJASN

Neurologia

✔ Absence of cerebrospinal fluid pleocytosis in encephalitis | CID

✔ Long-term outcomes after treatment of delirium during critical illness with antipsychotics - MIND-USA | NEJM

✔ Dexamethasone in adults with viral meningitis: An observational cohort study | CMI

POCUS

✔✔✔ Right Ventricular “Bubble Time” to Identify Patients With Right Ventricular Dysfunction | Annals of Emerg Med

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CASOS CLÍNICOS e SÉRIES DE CASOS

tabela de conteúdos ↟

Endocrinologia

A Rare Case of Dapagliflozin-Induced Hepatic Toxicity | RSPMI

Imuno-mediadas

Generalized Pustular Psoriasis: A Case Report | RSPMI

Infecciologia, Microbiologia & Antimicrobianos

Bowen's Disease in an HIV-Positive Patient | SPMI

Neurologia

Scolex on the Brain: Intraventricular Neurocysticercosis | Annals of Internal Medicine

Hyperostosis Frontalis Interna | Annals of Internal Medicine

Urologia

Giant Bladder Stones: A Severe Manifestation of Urolithiasis | RSPMI

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OPINIÃO

REVISÃO NÃO-SISTEMÁTICA / NARRATIVA

tabela de conteúdos ↟

Cardiovascular

✔✔✔ From ST-Segment Elevation MI to Occlusion MI: The New Paradigm Shift in Acute Myocardial Infarction | JACC

Meta-investigação & MBE

Four overlooked errors in ROC analysis: how to prevent and avoid | BMJ-EBM

Facilitating GRADE judgements about the inconsistency of effects using a novel visualisation approach | BMJ-EBM

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PERSPECTIVA

tabela de conteúdos ↟

Cardiovascular

✔ Current Clinical Guidelines Set Percutaneous Coronary Intervention Up to Fail? Insights From ORBITA-2 | Circulation

vs

✔ ORBITA Trials Are Not Justification to Promote "PCI-First" in Nonacute Myocardial Ischemic Syndromes | Circulation

✔ No false negative paradox in STEMI-NSTEMI diagnosis | BMJ-Heart

Infecciologia, Microbiologia & Antimicrobianos

✔ The Harm of Inappropriate Central Line Blood Cultures in Clinical Practice | JAMA Internal Medicine

Meta-investigação & MBE

School Mask Mandates and COVID-19: The Challenge of Using Difference-in-Differences Analysis | Annals of Intet Med

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NOTÍCIAS

tabela de conteúdos ↟

Psiquiatria

FDA Approves Novel Schizophrenia Drug | JAMA Network Open

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✔✔✔ FOAMed

tabela de conteúdos ↟

Cardiovascular

PRAECISely Predicting Preeclampsia | NephJC

Doente crítico/urgente

PROFUNDUS – POCUS-Plus for Aortic Syndromes | Journal Feed - EJIM

SGEM#454: I JUST DIED IN YOUR ARMS TONIGHT – D-DIMER FOR ACUTE AORTIC SYNDROMES | RebelEM

Clinical Conundrums: Should Ketamine be Preferred Over Etomidate in RSI? | RebelEM

The Ducanto Catheter—It Sucks! | RebelEM

Remote Consult Protocols for Retinal Artery Occlusion: A Visionary Approach in Emergency Care? | RebelEM

Liberal or restrictive transfusion in brain injury (The HEMOTION trial) | First10EM

Geral, Geriatria & Paliativos

TFP 375 Pharm for Fibro: Can antidepressants ease the pain?

Infecciologia, Microbiologia & Antimicrobianos

SGEM#452: I’M STILL STANDING – AFTER THE ALLERGY CHALLENGE | TheSGEM

Meta-investigação & MBE

Open and Ongoing Peer Review: A New Model for Scientific Research | St. Emlyn's

Nefrologia

Finerenone Finally Finishing off Spironolactone? | NephJC

KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease | NephJC

The KDIGO 2024 CKD Guidelines: part 2 | NephJC

Shedding Light on the Dense Matter of C3 Glomerulopathy | NephJC

Healing, Hype, or Harm: The NefIgArd trial at 2-years follow-up | NephJC

Nephrology needs COURAGE | PBF

POCUS

Biplane Needle Guidance for Central Lines | US Gel

Serratus Anterior Plane Blocks for rib fractures in the Emergency Department | St. Emlyn's

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